Prohormones

The K.I.S.S Approach

There is no question that Pro Hormones are the hottest selling sport supplements on the market.
During my years coaching major college and professional football, time after time, I learned the incredible value of the K.I.S.S. approach to performance, exercise and health. Keep It Simple Stupid. After more than two years of watching thousands of people (inculding myself) try multiple different Prohormone programs, I think it is finally time to apply the K.I.S.S. principles to Prohormones.

The K.I.S.S. approach is long overdue since there is no question that Prohormones are the hottest selling sport supplements on the market. The reason is simple; they have big time effects on muscle growth and on athletic performance. As their popularity soars, manufacturers are making these products extremely confusing. Every day a new product hits the market. Unless you are a biochemist, it is tough to separate the science from the science fiction.
Basically there are 5 popular separate products being sold either individually or in some combination with each other. They are as follows:

Androstenedione

4-Androstenediol

5-Androstenediol

19- Norandrostenedione

19-Norandrostenediol

You can readily see that these products can be grouped by their prefix; Andro vs. Norandro or by their suffix; dione vs. diol.

First we will discuss the Andro vs. Norandro debate.
Androstenedione and 4-Androstenediol are metabolites of DHEA but huge improvements biochemically. They are direct precursors to testosterone, meaning, there is only one enzyme needed to change them to testosterone. The conversion occurs quickly and the testosterone spike degrades fairly rapidly, most often, within hours.

5-Androstenediol is a precursor to Methandriol a very anabolic hormone that is commonly associated with veterinary steroids such as Winstrol V. 5-Andro has the additional properties of increasing the effects of all prohormones and decreasing muscle wasting cortisol.

19-Norandrostene (dione or diol), simply stated, it is an andro molecule without any carbon at the 19th position. Without carbon added, norandro cannot be converted to testosterone. Instead, it is converted to nortestosterone, in other words, the hormone nandrolone. Nandrolone is a highly anabolic hormone as well and has a high affinity
for steroid receptors meaning it stays attached much longer (up to 2-3 weeks). As a result, Norandro's nitrogen retentive and muscle enhancing effects peak less high but last far longer when compared to andro.

The second dimension for comparison is the "diones" vs. the "dioles."

On the biochem 101 blackboard, the "diols" appear to have much better conversion rates in the body than do the "diones." But in the real world, unquestionably, the opposite is true.
Based on a vast amount of feedback from athletes, androstenedione and 19-norandrostenedione are considered to be far superior to 4-Androstenediol and 19-norandrostenediol with respect to their anabolic effects.

Why? There are many different theories bouncing around out there to explain this fact but the most obvious is referred to as the enzyme availability theory.

Here is a chart on which enzyme is used to convert each of the individual substances:

Androstenedione
17 Hydroxysteroid dehydrenase

19- Norandrostenedione
17 Hydroxysteroid dehydrenase

4-Androstenediol

3 Hydroxysteroid dehydrenase

19-Norandrostenediol
3 Hydroxysteroid dehydrenase

5-Androstenediol
An Isomerase Enzyme

As you can see, all diones are converted using the 17 enzyme while diols use the 3 enzyme. While no one is sure if the body has more 17 enzymes than 3 enzymes, it is known that there are different types of 17 enzymes which reside in different organs (i.e. the liver, the testes). It is widely believed that it is the additive availability of these various 17 enzymes which cause the diones to have more biochemical effectiveness compared to that of the diols.

So which are better? Based on a huge number of real world observations and on the K.I.S.S. principle, I recommend the following:

Androstenedione: 200 mgs. before training; 100 mgs. after training & on off days
19-Norandrostenedione: 100 mgs. after training and 100 mgs. on off days

Personally, I use two Outlaw Bioscience products to achieve this:
Outlaw Androstenedione 100 mg. caps; 60’s
19 Norandrostenedione Complex 100 mg. caps; 60’s

Personally, we would suggest one of the following two programs for maximal gains:

K.I.S.S. Ten Week Program
1 bottle each; $29.95 (retail $67.05)

1 bottle Outlaw Androstenedione (2 caps before training)

2 bottles Outlaw Norandrostenedione (2 caps after training and 2 on off days)

Betterbodz Special $29.95 (Suggested Retail $67.05)
Buy 4 Programs for $89.00

Call 1-800-335-6740 to order

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